Effect of selenium dioxide on the testes of rat.

نویسندگان

  • A R Chowdhury
  • H Venkatakrishna-Bhatt
چکیده

Selenium dioxide was administered (ip) to albino male rats (200 +/- 5 g) in increasing doses (2, 6 and 10 micrograms/rat, daily) for 90 days. Histologic and histometric study showed that there was dose dependent injury to testes. No cellular deformation was observed following 2 micrograms-dose; whereas 6 micrograms-dose caused significant damage of gametogenic cells. At a dose of 10 micrograms, there was a significant testicular degeneration along with testicular atrophy.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Histopathological Effects of Titanium Dioxide Nanoparticles and The Possible Protective Role of N-Acetylcysteine on The Testes of Male Albino Rats

Objective Titanium dioxide (TiO2) is a white pigment which is used in paints, plastics, etc. It is reported to induce ‎oxidative stress and DNA damage. The N-acetylcysteine (NAC) was used to fight oxidative stress-induced ‎damage in various tissues. The aim of this study was to evaluate the toxic effects of TiO2 nanoparticles by oral ‎administration and the protective role of NAC on testes of a...

متن کامل

P-18: Effect of Royal Jelly on Oxidative Stress Marker in Testes Tissue in Streptozotocin-Induced Diabetic Rat

Background: Chronic diabetes mellitus is accompanied with enhanced oxidative stress and reduce the activity of antioxidant defense system. Due to significant role of enhanced oxidative stress in development of testes damage in diabetices, this study was conducted to evaluate the effect of royal jelly on oxidative stress marker in testis tissue of diabetic rats. Materials and Methods: In this ex...

متن کامل

Protective effects of vitamin E and selenium on spermatogenesis in adult male rat insulin-resistant

Background & Objective: Diabetes mellitus is a metabolic disease and is a multifactorial disorder characterized by chronic hyperglycemia resulting from impaired insulin secretion and insulin factional or both. In this study, the protective role of vitamin E and sodium selenite in preventing the harmful effects of insulin resistance (diabetes type 2) on spermatogenesis was studied.   Materials &...

متن کامل

Effect of methimazole-induced hypothyroidism on serum levels of LH and testosterone and weights of testes and thyroid gland in rat

Introduction: Thyroid hormones play an important role in the regulation of metabolism, maturity and reproduction. Thyroid dysfunction affects almost all endocrine glands such as pituitary and testis. The aim of this study was to investigate alterations of testosterone and luteinizing hormone (LH) serum levels as well as weights of thyroid gland and testes in methimazole (MMI)-induced hypothy...

متن کامل

Effect of Different Levels of Nano-selenium on Performance, Blood Parameters, Immunity and Carcass Characteristics of BroilerChickens

The aim of the present study was to test the hypothesis that nano- seleniuminclusion in broilers’ diets can improve productivity and metabolic functions of broilers.Feed and water were provided ad libitum. A total of 180 one-day old male Ross 308 chicks were randomly assigned to six groups based on a completely randomized design, each with three replicates of 10 birds. One of the groups served ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Indian journal of physiology and pharmacology

دوره 27 3  شماره 

صفحات  -

تاریخ انتشار 1983